NIST 800-53
U.S. federal catalog of security and privacy controls
ISO 28000
International standard for supply chain security management systems
Quick Verdict
NIST 800-53 provides comprehensive security/privacy controls for information systems, while ISO 28000 establishes a management system for supply chain security. Federal entities adopt 800-53 for compliance; logistics firms use 28000 for resilience and certification.
NIST 800-53
NIST SP 800-53 Rev. 5 Security Controls
Key Features
- 20 control families integrating security and privacy
- Outcome-based controls for flexible, risk-informed implementation
- Tailorable baselines for low/moderate/high impact levels
- Dedicated supply chain risk management family
- OSCAL machine-readable formats enabling automation
ISO 28000
ISO 28000:2022 Security management systems – Requirements
Key Features
- Risk-based approach to supply chain security threats
- PDCA cycle for continual improvement and resilience
- Supplier and third-party interdependency management
- Integration with ISO 27001, 22301 via High Level Structure
- Performance KPIs, internal audits, and certification pathway
Detailed Analysis
A comprehensive look at the specific requirements, scope, and impact of each standard.
NIST 800-53 Details
What It Is
NIST SP 800-53 Rev. 5, titled Security and Privacy Controls for Information Systems and Organizations, is a comprehensive control catalog and framework for protecting systems. Its primary purpose is providing flexible safeguards for confidentiality, integrity, availability, and privacy risks, using a risk-based, outcome-oriented approach integrated with the Risk Management Framework (RMF).
Key Components
- 20 control families (e.g., AC, AU, SR, PT) with over 1,100 base controls and enhancements.
- Baselines in SP 800-53B for low/moderate/high impact, plus privacy baseline.
- Tailoring, overlays, parameters for customization; OSCAL for machine-readable formats.
- Compliance via **RMF lifecyclecategorize, select, implement, assess, authorize, monitor.
Why Organizations Use It
- Meets FISMA/OMB A-130 mandates for federal systems/contractors.
- Enhances risk management, resilience, reciprocity of evidence.
- Builds trust, enables FedRAMP, market differentiation; voluntary for private sector.
Implementation Overview
- Phased RMF process: categorize per FIPS 199, select/tailor baselines, automate evidence.
- Applies to federal, contractors, critical infrastructure; requires audits, continuous monitoring.
ISO 28000 Details
What It Is
ISO 28000:2022 is an international certification standard specifying requirements for establishing, implementing, maintaining, and improving a security management system (SMS) focused on supply chain security and resilience. It uses a risk-based, PDCA (Plan-Do-Check-Act) approach to manage threats like theft, sabotage, and disruptions across supply chains.
Key Components
- Clauses 4-10 cover context, leadership, planning, support, operation, performance evaluation, and improvement.
- Emphasizes risk assessment, controls (physical, personnel, procedural), supplier governance, and incident response.
- Built on ISO High Level Structure (HLS) for integration with ISO 9001, 27001, 22301.
- Optional third-party certification via accredited bodies per ISO 28003.
Why Organizations Use It
- Mitigates operational risks, reduces incidents, lowers insurance costs.
- Meets contractual, regulatory (e.g., C-TPAT), and trade facilitation needs.
- Enhances resilience, market access, stakeholder trust, and competitive edge in logistics, manufacturing, pharma.
Implementation Overview
- Phased: scoping, gap analysis, risk treatment, deployment, audits, certification (6-36 months scalable by size).
- Applies to all sizes/industries with supply chains; involves mapping, training, KPIs, continual improvement.
Key Differences
| Aspect | NIST 800-53 | ISO 28000 |
|---|---|---|
| Scope | Information systems security/privacy controls | Supply chain security management system |
| Industry | Federal, contractors, critical infrastructure globally | Logistics, manufacturing, any supply chain sector |
| Nature | Voluntary control catalog with baselines | Voluntary management system certification standard |
| Testing | RMF assessments, continuous monitoring via 800-53A | Internal audits, management review, certification audits |
| Penalties | No direct penalties, contract/FedRAMP loss | No legal penalties, certification revocation |
Scope
Industry
Nature
Testing
Penalties
Frequently Asked Questions
Common questions about NIST 800-53 and ISO 28000
NIST 800-53 FAQ
ISO 28000 FAQ
You Might also be Interested in These Articles...

SOC 2 Trust Services Criteria in Plain English: Side-by-Side Decoder for Security, Availability, and Beyond
Decode AICPA Trust Services Criteria from auditor jargon to plain English with side-by-side tables, analogies & TL;DRs. CISOs & founders: implement SOC 2 contro

5 Ways Modern Compliance Software Makes Evolving Regulations Your Strategic Advantage
Discover 5 ways modern compliance software turns evolving regulations into strategic advantage. Automate monitoring, cut 3x non-compliance costs, stay audit-rea

Top 10 Reasons ISO 27701 is the Ultimate Privacy Boost for Your ISO 27001 ISMS in 2025
Extend ISO 27001 with ISO 27701 for ultimate privacy governance amid GDPR & AI regs. Discover top 10 advantages like integrated audits to future-proof your ISMS
Run Maturity Assessments with GRADUM
Transform your compliance journey with our AI-powered assessment platform
Assess your organization's maturity across multiple standards and regulations including ISO 27001, DORA, NIS2, NIST, GDPR, and hundreds more. Get actionable insights and track your progress with collaborative, AI-powered evaluations.
Check out these other Gradum.io Standards Comparison Pages
UL Certification vs IFS Food
Explore UL Certification vs IFS Food: NRTL safety marks & testing vs GFSI audits. Key differences, benefits & strategies for compliance success. Optimize now!
TOGAF vs GLBA
Compare TOGAF vs GLBA: EA framework meets financial privacy law. Discover key differences, compliance strategies & implementation tips for IT leaders. Optimize now!
CAA vs SQF
Compare CAA vs SQF: Clean Air Act emissions rules meet SQF food safety standards. Uncover key differences, compliance strategies & best practices for industry leaders. Boost your ops now!